生物
拟南芥
油菜素甾醇
细胞生物学
信号转导
免疫系统
先天免疫系统
拟南芥
免疫受体
蛋白酵素
植物免疫
生物化学
遗传学
突变体
基因
酶
作者
Qiuyi Li,Jing Shao,Mingyu Luo,Desheng Chen,Dingzhong Tang,Hua Shi
出处
期刊:Plant Science
[Elsevier]
日期:2024-02-01
卷期号:: 112033-112033
被引量:2
标识
DOI:10.1016/j.plantsci.2024.112033
摘要
The receptor-like cytoplasmic kinase BRASSINOSTEROID-SIGNALING KINASE1 (BSK1) interacts with pattern recognition receptor (PRR) FLAGELLIN SENSING2 (FLS2) and positively regulates plant innate immunity in Arabidopsis thaliana. However, the molecular components involved in BSK1-mediated immune signaling remain largely unknown. To further explore the molecular mechanism underlying BSK1-mediated disease resistance, we screened two cysteine proteases, RESPONSE TO DEHYDRATION 19 (RD19) and RD19-LIKE 2 (RDL2), as BSK1-binding partners. Overexpression of RD19, but not RDL2, displayed an autoimmune phenotype, presenting programmed cell death and enhanced resistance to multiple pathogens. Interestingly, RD19-mediated immune activation depends on BSK1, as knockout of BSK1 in RD19-overexpressing plants rescued their autoimmunity and abolished the increased resistance. Furthermore, we found that BSK1 plays a positive role in maintaining RD19 protein abundance in Arabidopsis. Our results provide new insights into BSK1-mediated immune signaling and reveal a potential mechanism by which BSK1 stabilizes RD19 to promote effective immune output.
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