微量营养素
肠道菌群
生物利用度
贫血
缺铁性贫血
缺铁
肠道微生物群
微量营养素缺乏
生理学
膳食铁
微生物群
生物
食品科学
免疫学
医学
内科学
生物信息学
病理
作者
Bolun Sun,Beibei Tan,Panxue Zhang,Lianlian Zhu,Huamao Wei,Tao Huang,Chao Li,Wenge Yang
出处
期刊:Food & Function
[The Royal Society of Chemistry]
日期:2024-01-01
卷期号:15 (3): 1144-1157
被引量:1
摘要
Iron deficiency anemia (IDA) caused by micronutrient iron deficiency has attracted global attention due to its adverse health effects. The regulation of iron uptake and metabolism is finely controlled by various transporters and hormones in the body. Dietary iron intake and regulation are essential in maintaining human health and iron requirements. The review aims to investigate literature concerning dietary iron intake and systemic regulation. Besides, recent IDA treatment and dietary iron supplementation are discussed. Considering the importance of the gut microbiome, the interaction between bacteria and micronutrient iron in the gut is also a focus of this review. The iron absorption efficiency varies considerably according to iron type and dietary factors. Iron fortification remains the cost-effective strategy, although challenges exist in developing suitable iron fortificants and food vehicles regarding bioavailability and acceptability. Iron deficiency may alter the microbiome structure and promote the growth of pathogenic bacteria in the gut, affecting immune balance and human health.
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