杀虫剂
环境友好型
农药残留
化学
毒理
生物技术
生物
农学
生态学
作者
Changcheng An,Bingna Huang,Jiajun Jiang,Xinyue Wang,Ningjun Li,Huihui Liu,Yue Shen,Changjiao Sun,Shenshan Zhan,Xingye Li,Chong Wang,Zhanghua Zeng,Haixin Cui,Qingjun Wu,Youjun Zhang,Zhiling Guo,Peng Zhang,Iseult Lynch,Jin‐Ming Gao,Yan Wang
出处
期刊:ACS Nano
[American Chemical Society]
日期:2023-12-22
卷期号:18 (1): 662-679
被引量:10
标识
DOI:10.1021/acsnano.3c08854
摘要
Developing an environmentally friendly and safe nanodelivery system is crucial to improve the efficacy of pesticides and minimize environmental and health risks. However, preparing a completely water-based nanopesticide without using harmful solvents is a technical challenge. In this study, a water-based nanodelivery pesticide system was constructed to improve the efficacy and safety of Emamectin Benzoate (EB). A specific surfactant, 29-(4-(5-hydroxynonan-5-yl)phenoxy)-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol (SurEB) was designed and synthesized to form a water-based nanodelivery system (EBWNS) with EB. Molecular dynamics simulations revealed the self-assembly and interaction forces between SurEB and EB in water, providing insights into the formation mechanism of EBWNS nanoparticles. The nanodelivery system showed the prolonged effectivity of EB with reduced degradation and demonstrated a good control efficacy for multiple target pests, such as red spider mite, beet armyworm larvae (Lepidoptera: Noctuidae), and rice stem borers (Chilo suppressalis). Toxicology tests on various objects demonstrated that the EBWNS has low toxicity for seeds, HaCaT cells, zebrafish, earthworm, and E. coli. This study provides a distinctive perspective for developing environmentally friendly nanopesticide formulations, which clarified a water-based treatment method for specific lipid-soluble pesticides. The water-based nanodelivery pesticide system has the potential to improve the efficacy and safety of pesticides in the process of field applications.
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