连翘
牙密螺旋体
密螺旋体
牙周炎
连翘
慢性牙周炎
微生物学
牙髓坏死
牙髓(牙)
医学
单纯疱疹病毒
生物
免疫学
牙科
牙龈卟啉单胞菌
病理
病毒
梅毒
金银花
替代医学
中医药
人类免疫缺陷病毒(HIV)
作者
Sheila Alexandra Belini Nishiyama,Viviane Nakano,Gustavo Velásquez-Meléndez,Mário Júlio Ávila-Campos
出处
期刊:Canadian Journal of Microbiology
[Canadian Science Publishing]
日期:2008-04-01
卷期号:54 (4): 326-330
被引量:26
摘要
Viral and bacterial associations appear to be implicated in the development of periodontal infections. Little information is available describing the periodontopathic agents in root canals with necrotic pulp. In this study, the occurrence and the combinations among herpes simplex virus type 1 (HSV-1) and Dialister pneumosintes , Tannerella forsythia , and Treponema denticola in patients with chronic periodontitis and necrotic pulp were evaluated. Clinical samples from healthy subjects and patients with periodontal or pulp infections were analyzed using a nested polymerase chain reaction PCR to detect HSV and PCR to detect the 3 periodontal bacteria. The presence of Tannerella forsythia and Treponema denticola was observed in healthy, periodontitis, and necrotic pulp patients. HSV was observed in periodontitis and necrotic pulp patients, and no healthy subject harbored D. pneumosintes or HSV. The occurrence of Tannerella forsythia was not statistically significant in patients with necrotic pulp (P = 0.704). Periodontal bacteria were observed varying from 10.3% to 20.7% in periodontitis and necrotic pulp patients. The presence of Treponema denticola – HSV association was predominant in patients showing necrotic pulp (24.1%); however, HSV alone was observed in one patient with periodontitis and in another patient with necrotic pulp. The presence of double association among bacteria or bacteria – HSV could indicate a role in both periodontitis and necrotic pulp, and Tannerella forsythia – Treponema denticola – HSV and Tannerella forsythia – D. pneumosintes – Treponema denticola – HSV associations might be important in periodontitis.
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