Magnetic mesoporous carbonated hydroxyapatite microspheres with hierarchical nanostructure for drug delivery systems

Magnetic mesoporous carbonated hydroxyapatite microspheres have been fabricated hydrothermally by using CaCO3/Fe3O4 microspheres as sacrificial templates. The high drug-loading capacity and sustained drug release property suggest that the multifunctional microspheres have great potentials for bone-implantable drug-delivery applications.