冷漠
评定量表
天花板效应
克朗巴赫阿尔法
心理学
帕金森病
物理疗法
物理医学与康复
医学
心理测量学
内科学
疾病
临床心理学
精神科
认知
发展心理学
病理
替代医学
作者
David A. Gallagher,Christopher G. Goetz,Glenn T. Stebbins,Andrew J. Lees,Anette Schrag
摘要
Abstract The UPDRS has been the main outcome measure in studies of PD. Modifications have been made to improve scale properties and represent the breadth of manifestations of PD, particularly nonmotor symptoms (NMS), resulting in the Movement Disorder Society's revision of the UPDRS (MDS‐UPDRS). This study was undertaken to determine the validity of MDS‐UPDRS Part I (nonmotor experiences of daily living). The MDS‐UPDRS and a number of validated scales for the NMS in PD were used in 94 patients with PD from Hoehn and Yahr stage I to V. We assessed reliability, floor and ceiling effects, and correlations with validated scales for the nonmotor symptoms of PD. MDS‐UPDRS Part I showed high internal consistency (Cronbach's alpha: 0.85), small floor and ceiling effects (2% floor and 0% ceiling effect), and good concurrent validity (correlation with the original UPDRS Part I: r = 0.81, P < 0.001). The standardized z‐score of the MDS‐UPDRS Part I score demonstrated high convergent validity with the composite z‐score of nonmotor scales (r = 0.89, P < 0.0001), and the two subscores based on the original factor analysis of Part I also had high correlations with the composite z‐scores of corresponding nonmotor scales (depression, anxiety, apathy factor score: r = 0.72, P < 0.0001; other nonmotor features factor score: r = 0.87, P < 0.0001). Our data demonstrate that the MDS‐UPDRS Part I total score has a strong relationship with a composite score of validated scales for the nonmotor aspects of PD. © 2011 Movement Disorder Society
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