The COMPLIANCE 360° Trial: a randomized, prospective, multicenter, pilot study comparing acute and long-term results of orbital atherectomy to balloon angioplasty for calcified femoropopliteal disease.

医学 再狭窄 血管成形术 气球 动脉切除术 支架 靶病变 狭窄 病变 临床终点 放射科 切割气球 外科 辅助治疗 随机对照试验 内科学 经皮冠状动脉介入治疗 心肌梗塞
作者
Raymond Dattilo,Stevan I. Himmelstein,Robert Cuff
出处
期刊:PubMed 卷期号:26 (8): 355-60 被引量:114
链接
标识
摘要

This study compares treatment results of orbital atherectomy (OA) vs balloon angioplasty (BA) for calcified femoropopliteal (FP) disease. BA for calcified FP disease is associated with increased dissection rates and suboptimal results. OA is hypothesized to decrease these acute complications via lesion compliance change.Fifty patients (65 lesions) with calcified FP disease were randomized to OA plus BA vs. BA alone and followed for 12 months. The primary endpoint was freedom from target lesion revascularization (TLR), including adjunctive stenting, or restenosis as evidenced by duplex ultrasound at 6 months.Mean maximum balloon pressure was 4.0 atm in the OA arm vs. 9.1 atm in the BA arm (P<.001). In subjects with residual stenosis >30%, the operator chose to stent 2/38 lesions (5.3%) in the OA arm vs 21/27 lesions (77.8%) in the BA arm (P<.001). Freedom from TLR (including adjunctive stenting) or restenosis was achieved in 77.1% of lesions in the OA group vs. 11.5% in the BA group (P<.001) at 6 months, and 81.2% vs. 78.3% at 12 months, excluding adjunctive stenting (P>.99).Compared to BA alone, OA plus BA yields better luminal gain by improving lesion compliance and decreases adjunctive stenting in the treatment of calcified FP disease. At 12 months, the occurrence of TLR or restenosis was similar in both groups despite the large disparity in stent usage at the time of initial treatment.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Ava应助扶桑采纳,获得10
3秒前
小蘑菇应助ht采纳,获得10
4秒前
velen完成签到,获得积分10
6秒前
qwe完成签到,获得积分10
8秒前
豪大大12138完成签到,获得积分10
8秒前
大个应助刘shuchang采纳,获得10
9秒前
Jasper应助欢呼山雁采纳,获得10
9秒前
10秒前
13秒前
Flowers完成签到,获得积分10
13秒前
yuyu发布了新的文献求助10
14秒前
囧囧应助王涛采纳,获得30
15秒前
打打应助loong采纳,获得10
16秒前
16秒前
16秒前
坚定自信发布了新的文献求助10
17秒前
adonis_lu完成签到,获得积分10
17秒前
skr发布了新的文献求助10
18秒前
wangch198201发布了新的文献求助10
19秒前
111完成签到 ,获得积分10
20秒前
香蕉觅云应助4848采纳,获得10
21秒前
善学以致用应助LYY采纳,获得10
21秒前
影子发布了新的文献求助10
22秒前
NexusExplorer应助范范采纳,获得30
22秒前
倚栏听风完成签到 ,获得积分10
22秒前
海棠朵朵完成签到 ,获得积分10
23秒前
yuyu完成签到,获得积分10
26秒前
柯一一应助坚定自信采纳,获得10
28秒前
ding应助坚定自信采纳,获得10
28秒前
29秒前
彭于晏应助ranj采纳,获得10
29秒前
31秒前
32秒前
李健的小迷弟应助执笔采纳,获得10
34秒前
FashionBoy应助执笔采纳,获得10
34秒前
酷波er应助执笔采纳,获得10
34秒前
36秒前
36秒前
欢呼山雁发布了新的文献求助10
36秒前
诺安成长混合完成签到,获得积分10
37秒前
高分求助中
Ophthalmic Equipment Market by Devices(surgical: vitreorentinal,IOLs,OVDs,contact lens,RGP lens,backflush,diagnostic&monitoring:OCT,actorefractor,keratometer,tonometer,ophthalmoscpe,OVD), End User,Buying Criteria-Global Forecast to2029 2000
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 588
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3962657
求助须知:如何正确求助?哪些是违规求助? 3508612
关于积分的说明 11142006
捐赠科研通 3241384
什么是DOI,文献DOI怎么找? 1791527
邀请新用户注册赠送积分活动 872916
科研通“疑难数据库(出版商)”最低求助积分说明 803517