甲酰胺类
异氰
化学
连续流动
流动化学
微流控
序列(生物学)
组合化学
有机化学
纳米技术
材料科学
生化工程
工程类
催化作用
生物化学
作者
Siddharth Sharma,Ram Awatar Maurya,Kyoung‐Ik Min,Guan‐Young Jeong,Dong‐Pyo Kim
标识
DOI:10.1002/anie.201303213
摘要
Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA = N,N-diisopropylethylamine.
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