铜
癌症治疗
平衡
铜毒性
化学
癌症研究
癌症
医学
细胞生物学
生物
内科学
有机化学
作者
Yingqiao Wang,Tao Tang,Yi Yuan,Nan Li,Xiaoqing Wang,Jian Guan
出处
期刊:ChemMedChem
[Wiley]
日期:2024-03-22
卷期号:19 (11)
被引量:4
标识
DOI:10.1002/cmdc.202400060
摘要
Copper (Cu), a crucial trace element in physiological processes, has garnered significant interest for its involvement in cancer progression and potential therapeutic applications. The regulation of cellular copper levels is essential for maintaining copper homeostasis, as imbalances can lead to toxicity and cell death. The development of drugs that target copper homeostasis has emerged as a promising strategy for anticancer treatment, with a particular focus on copper chelators, copper ionophores, and novel copper complexes. Recent research has also investigated the potential of copper complexes in cancer therapy.
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