A meta-analysis of the impact of pharmacist interventions on clinical outcomes in patients with type-2 diabetes

医学 药剂师 心理干预 科克伦图书馆 荟萃分析 2型糖尿病 随机对照试验 临床药学 内科学 梅德林 糖尿病 家庭医学 药店 护理部 内分泌学 政治学 法学
作者
Lirong Zhang,Huiting Lin,Wenhua Wu,Jie Zhuang,Longpeng Huang,Yiming Wang,Jia Liu,Congting Hu,Xiaoxia Wei
出处
期刊:Patient Education and Counseling [Elsevier BV]
卷期号:120: 108091-108091 被引量:5
标识
DOI:10.1016/j.pec.2023.108091
摘要

To evaluate the effects of pharmacist interventions in type-2 diabetes patients by collecting and evaluating literature. A systematic search was conducted across six databases, including CNKI, Wanfang Data, VIP, PubMed, Web of Science, and Cochrane Library, from January 2001 to January 2023. Randomized controlled trials evaluating the clinical outcomes of pharmacist interventions on type-2 diabetes patients were searched, and data were extracted and analysed by RevMan version 5.4 software. A total of 35 studies involving 4827 patients were included. Meta-analysis demonstrated that pharmacist interventions had an influence on improving patients' HbA1c (MD=−0.70), LDL-C (MD=−5.51), SBP (MD=−4.58), DBP (MD=−1.90], BMI (MD=−0.47) and FBG (MD=−19.82), but there was no evidence from the study that pharmacist interventions could significantly improve HDL-C (MD=−0.61), TC (MD=−5.12) or TG (MD=−3.14). In addition, medication adherence was significantly improved. Pharmacist interventions significantly improved HbA1c, BP, and LDL-C control levels, BMI, and medication adherence in type-2 diabetes patients, but there was no evidence from this study that pharmacist interventions significantly improved HDL-C, TC, or TG. Effective pharmacist interventions are important to improve type-2 diabetes patients' clinical outcomes.
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