半胱氨酸
亚硝化
硫醇
翻译后修饰
氧化还原
化学
亚硫酸
二硫键
生物化学
S-亚硝基化
氧化应激
反应性(心理学)
半胱氨酸代谢
酶
一氧化氮
医学
病理
有机化学
替代医学
作者
Jingjing Huang,Lindsy De Veirman,Frank Van Breusegem
摘要
Cysteine thiols are susceptible to various oxidative posttranslational modifications (PTMs) due to their high chemical reactivity. Thiol-based PTMs play a crucial role in regulating protein functions and are key contributors to cellular redox signaling. Although reversible thiol-based PTMs, such as disulfide bond formation, S-nitrosylation, and S-glutathionylation, have been extensively studied for their roles in redox regulation, thiol sulfinic acid (-SO
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