DNA损伤
DNA修复
低丙种球蛋白血症
生物
基因
DNA
组蛋白
免疫系统
功能（生物学）
细胞生物学
癌症研究
遗传学
抗体
作者
Brendan Mathias,David R O’Leary,Nermina Saucier,Faiz Ahmad,Lynn S. White,Le’Mark Russell,Marwan Shinawi,Matthew J. Smith,Roshini S. Abraham,Megan A. Cooper,Maleewan Kitcharoensakkul,Abby M. Green,Jeffrey J. Bednarski
标识
DOI：10.1016/j.jaci.2023.12.001
摘要
Patients with deleterious variants in MYSM1 have an immune deficiency characterized by B-cell lymphopenia, hypogammaglobulinemia, and increased radiosensitivity. MYSM1 is a histone deubiquitinase with established activity in regulating gene expression. MYSM1 also localizes to sites of DNA injury but its function in cellular responses to DNA breaks has not been elucidated.
科研通智能强力驱动
Strongly Powered by AbleSci AI
PDF的下载单位、IP信息已删除
(2025-6-4)
含糊的尔槐
无奈的碧彤
tuanheqi
风清扬
penxyy
tiptip
九月
无极微光
Wind
nino
浮浮世世
干净的琦
小宋
ceeray23
pluto
谈笑间
皖公网安备34019202002308
