Molecularly Imprinted Polymer Technology for the Advancement of Its Health Surveillances and Environmental Monitoring

Molecularly imprinted polymer (MIP) technology and its prospective used in the surveillance of the environment are the focus of this review article, which aims to give an in-depth understanding of the field. The approach of generating highly cross-linked polymeric structures with effective binding sites that precisely match the analyte of interest by templating with it is covered in the study as a means of producing biomimetic ligands. It also highlights the stability and robustness of MIPs, making them ideal for challenging environmental conditions. The originality of this paper lies in its exploration of various physical forms and synthesis techniques of MIPs, as well as the development of specialized MIPs to address specific challenges. It emphasizes the diverse applications of MIPs in environmental monitoring, including sample pretreatment, solid-phase extraction, microextraction, sensors, and chromatographic separations with the discussion on integration of MIPs with advanced analytical tools, highlighting the potential for enhancing the accuracy and reliability of environmental monitoring. Furthermore, the integration of MIPs with advanced analytical instruments opens up new possibilities for qualitative and quantitative evaluation of detection systems. Capillary electrochromatography and thin-layer chromatography are mentioned as the examples of analytical techniques that can be seamlessly integrated with MIPs. This integration enables improved accuracy and reliability in environmental monitoring, enhancing our understanding and protection of the environment. It not only explores the fundamentals of MIP technology but also delves into the synthesis methods, specialized MIPs, and integration with advanced analytical instruments. By providing this holistic view, the paper offers a valuable resource for researchers and practitioners interested in utilizing MIPs for environmental monitoring applications.