神经炎症
神经血管束
材料科学
原位
多细胞生物
纳米技术
生物医学工程
炸薯条
医学
炎症
生物
病理
计算机科学
细胞
内科学
有机化学
电信
化学
遗传学
作者
Jin‐Ha Choi,Hye Kyu Choi,Ki‐Bum Lee
标识
DOI:10.1002/adfm.202304382
摘要
The human neurovascular system is a complex network of blood vessels and brain cells that is essential to the proper functioning of the brain. In recent years, researchers have become increasingly interested in the role of this system in developing drugs to treat neuroinflammation. This process is believed to contribute to the development of several neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. While much remains to be learned about the precise mechanisms by which the neurovascular system interacts with the brain and how it can be targeted for therapeutic purposes, this area of research holds great promise for the future of neurology and medicine. Currently, creating neurovascular models begins with animal models, followed by testing on humans in clinical trials. However, the high number of medication failures that pass through animal testing indicates that animal models do not always reflect the outcome of human clinical trials. To overcome the challenges of neurovascular systems and the issues with animal models, we have developed a one-of-a-kind
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