骨髓增生异常综合症
医学
血液肿瘤
流式细胞术
造血
免疫分型
病理
干细胞
肿瘤科
免疫学
内科学
骨髓
生物
癌症
遗传学
作者
Xueyan Chen,Ulrika Johansson,Sindhu Cherian
标识
DOI:10.1016/j.cll.2023.06.006
摘要
Myelodysplastic syndromes/neoplasms (MDS) are a heterogeneous class of hematopoietic stem cell neoplasms characterized by ineffective hematopoiesis leading to peripheral cytopenias . This group of diseases is typically diagnosed using a combination of clinical, morphologic, and genetic criteria. Many studies have described the value of multiparametric flow cytometry (MFC) in the diagnosis, classification, and prognostication of MDS. This review summarizes the approach to MDS diagnosis and immunophenotypic characterization using MFC and describes the current state while highlighting future opportunities and potential pitfalls.
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