Functionalized Bone Implant Inspired by Lattice Defense Strategy: Grid Management, Precise and Effective Multiple‐Prevention of Osteomyelitis Recurrence and Promote Bone Regeneration

Osteomyelitis with a high recurrence rate. Timely-prevention can avoid severe consequence and death. However, conventional drug response-release has the disadvantages of unnecessary release and waste, causing ineffective prevention. Inspired by "Lattice-defense technology", gridding lesion areas and constructing a "Triggered-precise response-release system" may be an effective multiple-prevention method. Here, a new strict pH-triggered response drug controlled-release mechanism was proposed innovatively to construct a "Triggered-precise response-release system" and achieve multiple-effective prevention. PO