微泡
化学
清脆的
癌症
适体
癌细胞
纳米技术
计算生物学
分子生物学
小RNA
生物化学
生物
材料科学
基因
遗传学
作者
Xinyue Gu,Jingjing Zhang,Jing Liang,Xinyu Liu,Xiyu He,Xiang Ling Jin,Chenlong Yan,Lianhui Wang,Chunyuan Song
标识
DOI:10.1021/acs.analchem.4c03063
摘要
Cancer-derived exosomes carry a large number of specific molecular profiles from cancer cells and have emerged as ideal biomarkers for early cancer diagnosis. Accurate detection of ultralow-abundance exosomes in complex biological samples remains a great challenge. Herein, a novel SERS aptasensor powered by cascaded signal amplification of CRISPR/Cas13a
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