基质金属蛋白酶
Notch信号通路
间充质干细胞
信号转导
金属蛋白酶组织抑制剂
细胞生物学
基质金属蛋白酶9
医学
莫林
药理学
癌症研究
化学
内科学
生物
病理
作者
Yuan He,Xiao-Xuan Qin,Mingwei Liu,Wei Sun
标识
DOI:10.1016/j.joim.2024.11.002
摘要
Morin acts as an MMP-9 inhibitor to disrupt EndMT in atherosclerosis by limiting the activation of Notch-1 signaling. This study underscores morin's potential utility in the development of anti-atherosclerotic medication. Please cite this article as: He Y, Qin XX, Liu MW, Sun W. Morin, a matrix metalloproteinase 9 inhibitor, attenuates endothelial-to-mesenchymal transition in atherosclerosis by downregulating Notch-1 Signaling. J Integr Med. 2024; 22(6): 684-696.
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