Prevalence of Depression and Anxiety Among Adults With Chronic Pain

萧条(经济学) 焦虑 慢性疼痛 精神科 临床心理学 医学 心理学 经济 宏观经济学
作者
Rachel V. Aaron,Scott G. Ravyts,Nicolette D. Carnahan,Kavya Bhattiprolu,Nicole Harte,Claire C. McCaulley,Lauren Vitalicia,Andrew H. Rogers,Stephen T. Wegener,Joanne Dudeney
出处
期刊:JAMA network open [American Medical Association]
卷期号:8 (3): e250268-e250268
标识
DOI:10.1001/jamanetworkopen.2025.0268
摘要

Depression and anxiety are common among adults with chronic pain, but their prevalence is unclear. To evaluate the prevalence of depression and anxiety among adults with chronic pain and identify factors that moderate prevalence. A literature search was conducted of MEDLINE, Embase, PsycINFO, and Cochrane Library from January 2013 to October 2023. Studies reporting the prevalence of depression or anxiety using a validated assessment tool among adults with chronic pain (excluding chronic headache disorders). A total of 31 159 initial records were identified, and 5177 full texts were screened. Data were extracted per the Preferred Reporting Items for Systematic Reviews and Meta-analyses guideline using Covidence. Two independent reviewers completed abstract screening, full-text review, and data extraction and rated risk of bias. Random-effects meta-analyses were applied to pool prevalence, assess moderation, and compare prevalence of depression or anxiety among samples with chronic pain vs control samples. Prevalence of depression and anxiety based on clinically significant symptoms or diagnosis. The moderators of prevalence identified were pain condition, recruitment setting, continent, age, percentage female, and pain duration. The search identified 376 studies from 50 countries comprising 347 468 individuals (mean [SD] age, 51.3 [9.5] years; 70.0% female) with chronic pain. Among adults with chronic pain, clinical symptoms of depression were present in 39.3% (95% CI, 37.3%-41.1%; I2 = 98.9%), and clinical symptoms of anxiety were present in 40.2% (95% CI, 38.0%-42.4%; I2 = 99.0%). Prevalence differed by pain condition (highest among samples of people with fibromyalgia [depression, 54.0% (95% CI, 48.5%-59.4%); anxiety, 55.5% (95% CI, 50.4%-60.4%)]; lowest among samples of people with arthritis conditions [eg, osteoarthritis: depression, 29.1% (95% CI, 20.3%-39.7%); anxiety, 17.5% (95% CI, 6.6%-38.8%)]) and was highest among younger people (depression, β = -0.02 [95% CI, -0.03 to -0.01]; anxiety, β = -0.02 [95% CI, -0.03 to -0.01]) and women (depression, β = 0.69 [95% CI, 0.31-1.08]; anxiety, β = 0.90 [95% CI, 0.48-1.33]). With regard to diagnoses, 36.7% (95% CI, 29.0%-45.1%) had a major depressive disorder, and 16.7% (95% CI, 11.8%-23.2%) had generalized anxiety disorder. Women, younger people, and people with nociplastic pain (ie, pain arising from altered nociception without tissue damage) were most likely to have depression and anxiety. In this systematic review and meta-analysis of depression and anxiety among individuals with chronic pain, approximately 40% of adults had clinically significant depression and anxiety. Women, younger people, and people with nociplastic pain were most likely to have depression and anxiety. The co-occurrence of chronic pain with depression and anxiety is a significant public health concern necessitating routine screening in clinical settings, equitable access to specialty care, and innovative treatment development.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
科研通AI5应助悄悄采纳,获得10
1秒前
dryyu发布了新的文献求助10
1秒前
2秒前
高高凡霜发布了新的文献求助10
2秒前
恬淡虚无完成签到,获得积分10
4秒前
芋曦完成签到,获得积分10
4秒前
杏仁儿完成签到,获得积分10
5秒前
柒柒完成签到,获得积分10
6秒前
6秒前
6秒前
caixia完成签到,获得积分10
6秒前
浅兮完成签到,获得积分20
8秒前
杏仁儿发布了新的文献求助10
8秒前
9秒前
烨枫晨曦完成签到,获得积分10
9秒前
unique发布了新的文献求助10
10秒前
争取不秃顶的医学僧完成签到,获得积分10
10秒前
10秒前
科研通AI5应助科研通管家采纳,获得10
11秒前
11秒前
lxd应助科研通管家采纳,获得20
11秒前
科研通AI5应助科研通管家采纳,获得10
11秒前
NexusExplorer应助科研通管家采纳,获得10
11秒前
大个应助科研通管家采纳,获得10
11秒前
李健应助科研通管家采纳,获得10
11秒前
小二郎应助科研通管家采纳,获得10
11秒前
深情安青应助科研通管家采纳,获得10
11秒前
xs应助科研通管家采纳,获得10
11秒前
彭于晏应助科研通管家采纳,获得10
11秒前
FashionBoy应助科研通管家采纳,获得10
11秒前
浅兮发布了新的文献求助10
11秒前
科研通AI5应助科研通管家采纳,获得10
11秒前
领导范儿应助科研通管家采纳,获得10
11秒前
Ava应助嘤嘤怪采纳,获得10
11秒前
思源应助科研通管家采纳,获得10
11秒前
彭于晏应助科研通管家采纳,获得10
11秒前
11秒前
CodeCraft应助科研通管家采纳,获得10
11秒前
12秒前
高分求助中
Continuum Thermodynamics and Material Modelling 3000
Production Logging: Theoretical and Interpretive Elements 2700
Les Mantodea de Guyane Insecta, Polyneoptera 1000
Structural Load Modelling and Combination for Performance and Safety Evaluation 1000
Conference Record, IAS Annual Meeting 1977 720
電気学会論文誌D(産業応用部門誌), 141 巻, 11 号 510
有源雷达散射截面减缩——理论与应用 赫玛·辛格,拉凯什·莫汉·杰哈 500
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3569308
求助须知:如何正确求助?哪些是违规求助? 3140626
关于积分的说明 9438650
捐赠科研通 2841729
什么是DOI,文献DOI怎么找? 1561819
邀请新用户注册赠送积分活动 730660
科研通“疑难数据库(出版商)”最低求助积分说明 718179