医学
心脏病学
达帕格列嗪
内科学
后负荷
射血分数
肺楔压
心力衰竭
肺动脉
脉动流
肺动脉高压
血压
内分泌学
2型糖尿病
糖尿病
作者
Yogesh N.V. Reddy,Rickey E. Carter,Hidemi Sorimachi,Massar Omar,Dejana Popović,Alessio Alogna,Michael D. Jensen,Barry A. Borlaug
出处
期刊：JAMA Cardiology
[American Medical Association]
日期：2024-07-24
卷期号：9 (9): 843-843
被引量：3
标识
DOI：10.1001/jamacardio.2024.1914
摘要
Increases in pulmonary capillary wedge pressure (PCWP) during exercise reduce pulmonary artery (PA) compliance, increase pulsatile right ventricular (RV) afterload, and impair RV-PA coupling in patients with heart failure with preserved ejection fraction (HFpEF). The effects of the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin on pulmonary vascular properties and RV-PA coupling are unknown.
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