组合化学
芳基
化学
兴奋剂
受体
肽
药理学
立体化学
医学
生物化学
有机化学
烷基
作者
Nicholas R. Wurtz,Pravin S. Shirude,Daniel L. Cheney,John A. Lupisella,Amit K. Chattopadhyay,Vishweshwaraiah Baligar,Balaji Seshadri,Prakash Anjanappa,Andrew Q. Viet,Meriah N. Valente,Mei-Yin Hsu,Mojgan Abousleiman,Sanket Sarodaya,Debarati M. Tagore,Shailesh Dudhgaonkar,Sivaprasad Putlur,Elizabeth A. Dierks,Jacek Ostrowski,Ruth R. Wexler,Ricardo Garcı́a,Ellen K. Kick
标识
DOI：10.1021/acsmedchemlett.4c00172
摘要
We report the discovery and optimization of aryl piperidinone urea formyl peptide receptor 2 (FPR2) agonists from a weakly active high-throughput screening (HTS) hit to potent and selective agonists with favorable efficacy in acute
科研通智能强力驱动
Strongly Powered by AbleSci AI
彭于彦祖
oceanao
吃不饱星球球长
爱静静
tianzml0
iNk
Henry
HEIKU
iWatchTheMoon
子车茗
几酌
寻道图强
shinysparrow
互助遵法尚德
hujin
Jun
Singularity
苏卿
嗯哼
夏远航
皖公网安备34019202002308
