血管平滑肌
生物
钙化
内分泌学
内科学
癌症研究
细胞生物学
医学
平滑肌
作者
Wenqi Ma,Kangni Jia,Haomai Chen,Xu Hong,Zhigang Li,Hang Zhang,Hongyang Xie,Sun Hang,Yi Lei,Zhiyong Chen,Sheng‐Zhong Duan,Motoaki Sano,Keiichi Fukuda,Lin Lu,Fei Gao,Ruiyan Zhang,Xiaoxiang Yan
出处
期刊:Circulation Research
[Ovid Technologies (Wolters Kluwer)]
日期:2024-05-24
卷期号:134 (11): 1427-1447
被引量:2
标识
DOI:10.1161/circresaha.123.323699
摘要
Medial arterial calcification is a chronic systemic vascular disorder distinct from atherosclerosis and is commonly observed in patients with chronic kidney disease, diabetes, and aging individuals. We previously showed that NR4A3 (nuclear receptor subfamily 4 group A member 3), an orphan nuclear receptor, is a key regulator in apo (apolipoprotein) A-IV-induced atherosclerosis progression; however, its role in vascular calcification is poorly understood.
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