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Evaluation of chemotherapy‐induced cutaneous side effects in cancer patients

医学 粘膜皮肤区 副作用(计算机科学) 化疗 粘膜炎 癌症 皮肤病科 脱发 生活质量(医疗保健) 内科学 外科 疾病 计算机科学 护理部 程序设计语言
作者
Elif Demirci Saadet,İbrahim Tek
出处
期刊:International Journal of Dermatology [Wiley]
卷期号:61 (12): 1519-1526 被引量:7
标识
DOI:10.1111/ijd.16361
摘要

Cutaneous side effects are commonly seen in cancer chemotherapy. As new chemotherapy drugs are developed, the frequency and the diversity of these cutaneous side effects increase. For this reason, identification and management of these side effects are an important part of the treatment of cancer patients. This study aimed to investigate mucocutaneous side effects of conventional chemotherapy and targeted therapy agents that are used in cancer patients.In this cross-sectional study, 231 cancer patients, who received single or combination chemotherapy at the oncology department of our hospital between 2013 and 2020, were retrospectively reviewed, and mucocutaneous side effects we evaluated.The ages of the patients varied between 27 and 90 years with a median age of 60 years. Of the patients, 136 (58.9%) were women, and 95 (41.1%) were men. Combination chemotherapy was applied to 174 patients (71.9%). A total of 558 mucocutaneous side effects were present in 231 patients. The most common side effect was alopecia, which was observed in 158 patients (65.6%). This was followed by mucositis (39.4%), hand-foot syndrome (35.3%), papulopustular rash (22%), dermatitis (18.3%), xerosis (14.1%), nail disorders (12%), and others.Although chemotherapy-induced cutaneous side effects are not usually life-threatening, they may lead to the development of morbidity and discontinuance or termination of the treatment. Therefore, these side effects should be well managed to improve the quality of life of cancer patients.
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