经颅直流电刺激
磁刺激
医学
冲程(发动机)
初级运动皮层
神经学
物理医学与康复
运动皮层
康复
随机对照试验
脑刺激
物理疗法
刺激
重复措施设计
方差分析
内科学
精神科
工程类
统计
机械工程
数学
作者
Sutthikit Pipatsrisawat,Jakkrit Klaphajone,Kittipong Kitisak,Somporn Sungkarat,Pakorn Wivatvongvana
出处
期刊:BMC Neurology
[Springer Nature]
日期:2022-03-17
卷期号:22 (1)
被引量:5
标识
DOI:10.1186/s12883-022-02607-3
摘要
Strokes have recently become a leading cause of disability among Thai people. Non-invasive brain stimulation (NIBS) seems to give promising results in stroke recovery when combined with standard rehabilitation programs.To evaluate the combined effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) and cathodal transcranial direct current stimulation (tDCS) over the non-lesional primary motor cortex on upper limb motor recovery in patients with subacute stroke. No reports of a combination of these two techniques of NIBS were found in the relevant literature.This pilot study was a double-blinded, randomized controlled trial of ten patients with subacute stroke admitted to the Rehabilitation Medicine Inpatient Unit, Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University. They were randomized into two groups: five in an active and five in a sham intervention group. Fugl-Meyer's upper extremity motor score (FMA-UE) and Wolf Motor Function Test (WMFT) were used to assess motor recovery at baseline, immediately, and 1 week after stimulation.A two-way repeated ANOVA (mixed design) showed a significant improvement in FMA-UE scores in the active intervention group both immediately and 1 week after stimulation in comparison to the baseline, [time, F (2, 16) = 27.44, p < 0.001, time x group interaction, F (2, 16) = 13.29, p < 0.001]. Despite no statistical significance, a trend toward higher WMFT scores was shown in the active intervention group.A single session of low-frequency rTMS and cathodal tDCS over the non-lesional primary motor cortex may enhance upper limb motor recovery in patients with subacute stroke.
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