Cost effectiveness of dermatofibrosarcoma protuberans treated with Mohs micrographic surgery compared with wide local excision

Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive soft-tissue sarcoma that often presents with significant subclinical extension; consequently, it has a high rate of local recurrence when treated with wide local excision (WLE). 1 Gloster H.M. Dermatofibrosarcoma protuberans. J Am Acad Dermatol. 1996; 35 (quiz 375.): 355-374https://doi.org/10.1016/s0190-9622(96)90597-6 Abstract Full Text PDF PubMed Google Scholar For the treatment of DFSP, Mohs micrographic surgery (MMS) has consistently demonstrated improved outcomes compared to WLE. Thus, the National Comprehensive Cancer Network now recommends MMS as the treatment of choice. 2 Lowe G.C. Onajin O. Baum C.L. et al. A comparison of mohs micrographic surgery and wide local excision for treatment of dermatofibrosarcoma protuberans with long-term follow-up: the Mayo Clinic experience. Dermatol Surg. 2017; 43: 98-106https://doi.org/10.1097/DSS.0000000000000910 Crossref PubMed Scopus (79) Google Scholar ,3 Mai N. Lynn B. Schmults C. et al. NCCN Guidelines version 1.2022. Dermatofibrosarcoma Protuberans. National Comprehensive Cancer Network. Published online 2021. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1430Date accessed: December 28, 2021 Google Scholar