Diverse catalytic systems for nitrogen-heterocycle formation from O-acyl ketoximes

O -Acyl ketoximes has been proven to be versatile building blocks for practical construction of N -heterocycles. In the last few years, diverse catalytic systems have been discovered to enable efficient transformations of O -acyl ketoximes to a range of nitrogen-heterocycles. Herein, we summarized our recent examples of novel nitrogen-heterocycle formation with new function findings of O -acyl ketoximes through facile aerobic copper catalysis, metal-free N-O bond activation, multi-component assembly, and bis-annulations. From the green chemistry perspective, these works represent efficient methods with high atom economy, high selectivity, and minimized chemical waste. These findings also complement well to the previous mainly copper-based catalytic systems and more importantly enrich the oxime chemistry in organic synthesis. The mini-review is dedicated to showcase and discuss our recent progress in the development of catalytic systems for nitrogen-heterocycle formation from O -acyl ketoximes