生物
细菌
微生物学
免疫系统
噬菌体
计算生物学
基因
免疫学
遗传学
大肠杆菌
作者
Hugo Oliveira,Zuzanna Drulis‐Kawa,Hugo Oliveira
标识
DOI:10.1016/j.tim.2022.05.002
摘要
Bacteria are protected against the immune system of their human hosts, as well as against predators such as phages, by expressing diverse surface carbohydrates. Some phages produce specialized depolymerases which can degrade those carbohydrates. Here, we discuss the biological role of depolymerases and how they can be exploited to develop new therapeutic strategies against pathogens. Bacteria are protected against the immune system of their human hosts, as well as against predators such as phages, by expressing diverse surface carbohydrates. Some phages produce specialized depolymerases which can degrade those carbohydrates. Here, we discuss the biological role of depolymerases and how they can be exploited to develop new therapeutic strategies against pathogens.
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