Access to Isoquinolin‐1(2 H)‐ones and Pyridones by Cobalt‐Catalyzed Oxidative Annulation of Amides with Allenes

Abstract A cobalt‐catalyzed oxidative annulation of amides with allenes to provide isoquinolin‐1(2 H )‐ones and pyridones was explored. The new catalytic reaction proceeded through aminoquinoline‐directed C−H activation followed by unusual regioselective insertion, annulation, and isomerization. A variety of functionalized amides and allenes were converted into the corresponding products under mild reaction conditions.