Nickel‐Catalyzed Cross‐Coupling of Aryl Bromides with Tertiary Grignard Reagents Utilizing Donor‐Functionalized N‐Heterocyclic Carbenes (NHCs)

One, two or three? The utilization of sterically hindered alkyl substrates represents a major challenge of the present cross-coupling methodology. The nickel-catalyzed Kumada cross- coupling of tertiary alkyl Grignard reagents with aryl bromides allows this difficult reaction with numerous different substrates. Optimal results were obtained using sterically demanding, bifunctional N-heterocyclic carbene ligands.