Prediction of Microvascular Invasion of Hepatocellular Carcinoma: Preoperative CT and Histopathologic Correlation

医学 肝细胞癌 放射科 血管侵犯 病理 内科学
作者
Chen‐Te Chou,Ran‐Chou Chen,Wei‐Chan Lin,Chih‐Jan Ko,Chia‐Bang Chen,Yao‐Li Chen
出处
期刊:American Journal of Roentgenology [American Roentgen Ray Society]
卷期号:203 (3): W253-W259 被引量:146
标识
DOI:10.2214/ajr.13.10595
摘要

The objective of our study was to prospectively investigate whether nonsmooth margins detected on multiphasic CT images correlate with the presence and location of microvascular invasion (MVI) in hepatocellular carcinoma (HCC).A total of 102 patients with preoperative CT findings of solitary HCC were prospectively enrolled. Tumor size, tumor capsule, tumor margins, and peritumoral enhancement on preoperative CT images were assessed. Histopathologic results including the following were also recorded: tumor differentiation; liver fibrosis score; presence or absence of MVI; and, if present, the location of MVI. Correlation between tumor margin on preoperative CT images and histopathologic location of MVI was determined.Pathologic examination revealed MVI in 60 of the 102 HCC specimens. Although the results of the univariate analysis showed that tumor size, higher Edmondson-Steiner grade, and nonsmooth tumor margins were associated with MVI, multivariate analysis revealed that only nonsmooth margins correlated with the presence of MVI in HCC (p < 0.001). Of the 60 HCC specimens with histopathologic evidence of MVI, 40 exhibited focal nonsmooth margins. In addition, the locations of the nonsmooth margins and MVI were similar in 36 of the 40 specimens.Nonsmooth tumor margins correlated with the histopathologic presence and location of MVI. Therefore, nonsmooth margins detected on multiphasic CT may be predictive of MVI in HCC.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
去有风的地方完成签到 ,获得积分10
2秒前
上下完成签到 ,获得积分10
4秒前
王娟秀完成签到 ,获得积分10
5秒前
YL完成签到,获得积分10
7秒前
NexusExplorer应助小王采纳,获得10
8秒前
8秒前
sl完成签到,获得积分10
8秒前
CC完成签到,获得积分10
9秒前
自信松思完成签到 ,获得积分10
10秒前
荣枫完成签到,获得积分10
10秒前
10秒前
火火火木完成签到 ,获得积分10
11秒前
大模型应助妖孽宇采纳,获得10
11秒前
13秒前
积极行天发布了新的文献求助50
13秒前
受伤凌蝶发布了新的文献求助10
16秒前
fusucheng完成签到,获得积分10
17秒前
koi完成签到,获得积分20
17秒前
17秒前
聪明摩托完成签到,获得积分10
17秒前
阿纯完成签到,获得积分10
18秒前
19秒前
肱二头肌完成签到,获得积分10
20秒前
21秒前
小王发布了新的文献求助10
21秒前
多情自古空余恨完成签到,获得积分10
22秒前
Qionglin完成签到,获得积分10
24秒前
Bao完成签到 ,获得积分10
25秒前
25秒前
初夏微凉发布了新的文献求助30
25秒前
26秒前
书霂完成签到,获得积分10
26秒前
优秀含羞草完成签到,获得积分10
27秒前
宓沂完成签到,获得积分10
27秒前
vivre223完成签到,获得积分10
27秒前
量子星尘发布了新的文献求助10
28秒前
受伤凌蝶完成签到,获得积分10
29秒前
wenjiejiang完成签到,获得积分10
30秒前
30秒前
zly完成签到 ,获得积分10
31秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038388
求助须知:如何正确求助?哪些是违规求助? 3576106
关于积分的说明 11374447
捐赠科研通 3305798
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029