滋养层
细胞生物学
生物
Wnt信号通路
形态发生
信号转导
胎盘
遗传学
胎儿
怀孕
基因
作者
Jinhua Lu,Shuang Zhang,Haruo Nakano,David G. Simmons,Shumin Wang,Shuangbo Kong,Qiang Wang,Lianju Shen,Zhaowei Tu,Weixiang Wang,Bingyan Wang,Hongmei Wang,Yanling Wang,Johan H. van Es,Hans Clevers,Gustavo Leone,James C. Cross,Haibin Wang
出处
期刊:PLOS Biology
[Public Library of Science]
日期:2013-04-16
卷期号:11 (4): e1001536-e1001536
被引量:91
标识
DOI:10.1371/journal.pbio.1001536
摘要
Placenta formation during pregnancy requires chorioallantoic branching morphogenesis that involves establishing an amplifying feedback loop between Frizzled5 and Gcm1 to regulate branching initiation and trophoblast differentiation.
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