Asymmetric Intramolecular Diels–Alder Reaction Catalyzed by the Chiral Titanium Reagent

Abstract The highly enantioselective intramolecular Diels–Alder reaction is achieved using a catalytic amount of the chiral titanium reagent prepared from TiCl2(OPri)2 and the tartrate derived chiral 1,4-diol.