化学
背景(考古学)
金属环
纳米技术
化疗
光学成像
医学
物理
材料科学
内科学
X射线晶体学
生物
光学
古生物学
衍射
作者
Tuo Wei,Yuling Xu,Yifan Fan,Jun Li,Mingqiang Qiu,Xiaoxing Xiong,Xiangyang Li,Yao Sun
标识
DOI:10.1016/j.ccr.2021.214017
摘要
Platinum-based coordination chemistry has laid the foundation for the development of numerous metal complexes and provoked their applications in cancer chemotherapy. It is noteworthy that Pt(II) metallacyles/metallacages formed through coordination-driven self-assembly exhibit improved optical properties and superior anticancer efficacies in comparison with their precursors. To this end, the employment of metallacycles/metallacages as chemotherapy agents, imaging contrasts and multifunctional theranostic platforms has attracted tremendous attention. In this context, we provide an insight into the progression of Pt(II) metallacycles/metallacages from mono-chemotherapeutic agents to versatile imaging contrasts and theranostic platforms.
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