Agriculture and land use are major sources of greenhouse gas (GHG) emissions but previous estimates were either highly aggregate or provided spatial details for subsectors obtained via different methodologies. Using a model–data integration approach that ensures full consistency between subsectors, we provide spatially explicit estimates of production- and consumption-based GHG emissions worldwide from plant- and animal-based human food in circa 2010. Global GHG emissions from the production of food were found to be 17,318 ± 1,675 TgCO2eq yr−1, of which 57% corresponds to the production of animal-based food (including livestock feed), 29% to plant-based foods and 14% to other utilizations. Farmland management and land-use change represented major shares of total emissions (38% and 29%, respectively), whereas rice and beef were the largest contributing plant- and animal-based commodities (12% and 25%, respectively), and South and Southeast Asia and South America were the largest emitters of production-based GHGs. The quantification of greenhouse gas emissions related to food production and consumption is still largely hindered by the availability of spatial data consistent across sectors. This study provides a detailed account of emissions from land-use change, farmland, livestock and activities beyond the farm gate associated with plant- and animal-based foods/diets—culminating in local-, country- and global-level emissions from each major agricultural commodity.