海绵
真菌
曲霉
微生物学
化学
消炎药
生物
药理学
植物
作者
Trần Hồng Quang,Le Thi Vien,Lê Ngoc Anh,Nguyễn Thị Thanh Ngân,Trần Thị Hồng Hạnh,Nguyễn Xuân Cường,Nguyễn Hoài Nam,Châu Văn Minh
标识
DOI:10.1002/vjch.202000099
摘要
Abstract Chemical investigation of the marine sponge‐derived fungal strain Aspergillus sp. IMBC‐FP2.05 resulted in isolation of five compounds, including JBIR‐74 ( 1 ), homogentisic acid ( 2 ), methyl (2,5‐dihydroxyphenyl)acetate ( 3 ), 3‐chloro‐2,5‐dihydroxybenzyl alcohol ( 4 ), and p ‐hydroxybenzaldehyde ( 5 ). Their chemical structures were identified by comprehensive analyses of the 1D and 2D NMR and mass spectra in comparison with the previously reported data. Furthermore, nitric oxide (NO) inhibitory effects of the isolated compounds in LPS‐stimulated RAW264.7 cells were also reported.
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