Competitive inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase by ML‐236A and ML‐236B fungal metabolites, having hypocholesterolemic activity

FEBS LettersVolume 72, Issue 2 p. 323-326 Full-length articleFree Access Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity Akira Endo, Akira Endo Fermentation Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140, JapanSearch for more papers by this authorMasao Kuroda, Masao Kuroda Fermentation Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140, JapanSearch for more papers by this authorKazuhiko Tanzawa, Kazuhiko Tanzawa Fermentation Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140, JapanSearch for more papers by this author Akira Endo, Akira Endo Fermentation Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140, JapanSearch for more papers by this authorMasao Kuroda, Masao Kuroda Fermentation Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140, JapanSearch for more papers by this authorKazuhiko Tanzawa, Kazuhiko Tanzawa Fermentation Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140, JapanSearch for more papers by this author First published: December 31, 1976 https://doi.org/10.1016/0014-5793(76)80996-9Citations: 569AboutReferencesRelatedInformationPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessClose modalShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 A. Endo, M. Kuroda, Y. Tsujita, J. Antibiotics, (1976), in the press 2 M. Kuroda, A. Endo, Biochim. Biophys. Acta, 486, (1976), 70– 81. 3 R.A. Heller, R.G. Gould, Biochem. Biophys. Res. Commun., 50, (1973), 859– 865. 4 O.H. Lowry, N.J. Rosebrough, A.L. Farr, R.J. Randall, J. Biol. Chem., 193, (1951), 265– 275. Citing Literature Volume72, Issue2December 31, 1976Pages 323-326 ReferencesRelatedInformation Metrics All-time Citations: 569 Details FEBS Letters 72 (1976) 1873-3468 © 2015 Federation of European Biochemical Societies Publication History Issue Online: 19 October 2001 Version of Record online: 19 October 2001 Manuscript received: 15 November 1976