化学
二氯甲烷
普林斯反应
催化作用
烯醇
溶剂
卤素
路易斯酸
布朗斯特德-洛瑞酸碱理论
药物化学
有机化学
烷基
作者
Yi Yang,Pingjing Jia,Liu Su-ping,Wei Yu
标识
DOI:10.1002/cjoc.201100659
摘要
Abstract The Prins cyclization of enol ethers has been realized by employing BiX 3 (or FeX 3 ) as catalyst and TMSX (X=Br, Cl) as the halogen source. The presence of a tiny amount of water in the solvent dichloromethane played a key role for the reaction to proceed. The reaction is believed to be catalyzed by Lewis acid‐assisted Brønsted acids, which were generated in situ from MX 3 and water in the solvent.
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