Research advances in liver ischemia reperfusion injury

Hepatic ischemia reperfusion injury (IRI) is a continuous process of damage of liver cells, which could cause a series of clinic reactions. Early owing to IRI, organ failure reaches 10%, and easily leads to acute and chronic liver transplantation rejection. Therefore, study on the treatment method of IRI is very important. Decreasing the adverse effect of IRI could significantly increase the amount of successful liver transplantation. This paper will explore mainly on the pretreatment methods of IRI. Key words: Liver transplantation; Ischemia reperfusion injury; Pretreatment methods