Application of growth hormone in in vitro fertilization assisted pregnancy

At present, more and more infertile women need to use assisted reproductive technology to complete pregnancy. However, in the in vitro fertilization and embryo transfer (IVF-ET) process, some patients often have lower pregnancy success rate due to poor ovarian reactivity, poor follicular dysplasia and poor endometrial receptivity. Increased ovarian responsiveness, oocyte quality and endometrial receptivity to improve IVF-ET outcomes has become a common challenge for clinical and laboratory workers, which has become a major problem in the field of assisted reproduction. The main role of growth hormone is promoting the growth of whole body tissues and organs, especially bones and muscles. It can also regulate the metabolism of three major substances in the body, promote protein synthesis, inhibit fat metabolism, raise blood sugar, etc. At this stage, growth hormone also plays a huge role in female reproductive health, mainly in increasing the ovarian response to gonadotropins, optimizing follicle oocyte quality, improving embryo quality, increasing endometrial thickness and improving endometrial receptivity. This review focuses on the role of growth hormone in the female reproductive system, the applicable population and usage. Key words: Growth hormone; Ovarian reactivity; Oocyte quality; Endometrial receptivity; Applicable population; Usage