前药
生化工程
论证(复杂分析)
药品
财产(哲学)
计算机科学
动作(物理)
管理科学
风险分析(工程)
化学
药理学
工程类
认识论
医学
物理
哲学
量子力学
生物化学
作者
Vivekkumar K. Redasani,Sanjay B. Bari
标识
DOI:10.1016/b978-0-12-803519-1.00005-2
摘要
The various obstructions associated with drugs can be overcome by applying the concept of prodrugs. This helps in improvement of unwanted physicochemical properties of existing drugs and increases their therapeutic effectiveness. The various properties that can be improved include aesthetic and drug formulation properties. This chapter deals with the detailed outlook of such properties and a remedy to overcome it. Each and every physicochemical property is an argument of drug action. Brief explanatory data supported by examples help to understand the concept of prodrugs and serve their utility in medicinal chemistry in order to obtain good drug candidates.
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