医学
针灸科
可视模拟标度
随机对照试验
物理疗法
不利影响
蜂毒
慢性疼痛
Oswestry残疾指数
贝克抑郁量表
心情
生活质量(医疗保健)
腰痛
麻醉
背痛
萧条(经济学)
内科学
焦虑
精神科
替代医学
经济
护理部
病理
宏观经济学
动物
生物
作者
Byung-Kwan Seo,Kyungsun Han,Ojin Kwon,Dae-Jean Jo,Jun‐Hwan Lee
出处
期刊:Toxins
[MDPI AG]
日期:2017-11-07
卷期号:9 (11): 361-361
被引量:38
标识
DOI:10.3390/toxins9110361
摘要
Bee venom acupuncture (BVA) is an effective treatment for chronic low back pain (CLBP) through the pharmacological effects of bee venom and the simultaneous stimulation of acupoints. However, evidence of its efficacy and safety in humans remains unclear. Using a double-blind, randomized study, 54 patients with non-specific CLBP were assigned to the BVA and sham groups. All participants underwent six sessions of real or sham BVA for 3 weeks, in addition to administration of 180 mg of loxonin per day. The primary outcome, that is, “bothersomeness” derived from back pain, was assessed using the visual analog scale. Secondary outcomes included pain intensity, dysfunction related to back pain (Oswestry Disability Index), quality of life (EuroQol 5-Dimension), and depressive mood (Beck’s depression inventory). Outcomes were evaluated every week during the treatment period and followed up at weeks 4, 8, and 12. After 3 weeks of the treatment, significant improvements were observed in the bothersomeness, pain intensity, and functional status in the BVA group compared with the sham group. Although minimal adverse events were observed in both groups, subsequent recovery was achieved without treatment. Consequently, our results suggest that it can be used along with conventional pharmacological therapies for the treatment of CLBP.
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