Anti‐obesity Effect of Bamboo Salt In Vivo

This study was aimed to determine the anti‐obesity effect of bamboo salt in vivo . For this purpose, we divided C57BL/6 mice with various groups on the basis of the treatment (normal diet, high‐fat diet (HFD), HFD + purified salt treatment, HFD + solar salt treatment, HFD + bamboo salt treatment (1×, 3× and 9× baked), feeding mice of each salt‐fed group with the dosage corresponding with the concentration twice as high as recommended salt intake of human (5 g). After 8 weeks, we measured serum lipid profile (triglyceride and total cholesterol) and epididymal adipose tissue. Concomitant feeding of HFD and bamboo salt reduced the overall body weight, weight of epididymal adipose tissue and food efficacy ratio, compared with high‐fat diet group and/or other high‐fat diet + salt samples. Feeding of bamboo salt also lowered serum lipid profiles and ALT/AST in comparison with the high‐fat diet group. We also observed changes in expression of obesity‐related factors (C/EBPα, SREBP‐1c and FAS) and inflammation‐related factors (PPAR‐γ and IL‐6). Taken together, this study suggests that treatment of bamboo salt in mice might have a preventive effect on obesity.