球毛壳菌
真菌
节肢动物
毛壳
圆二色性
生物
立体化学
化学
微生物学
植物
古生物学
曲霉
作者
Weixi Gao,Rui Jiang,Hanxiao Zeng,Jie Cao,Zhengxi Hu,Yonghui Zhang
标识
DOI:10.1080/14786419.2022.2150846
摘要
Armochaetoglasins L (1) and M (2), two new cytochalasans, were isolated from the EtOAc extract of an arthropod-derived fungus Chaetomium globosum. Armochaetoglasin L (1) is a rare 19,20-seco-chaetoglobosin. Their structures were elucidated by NMR spectroscopy and comparison of their electronic circular dichroism (ECD) data. Compounds 1 and 2 were evaluated for anti-inflammatory activity against the NO production by using LPS-stimulated murine macrophage RAW264.7 cells and antibacterial activity against three drug-resistant microbial pathogens.
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