医学
心脏病学
内科学
射血分数
心肌梗塞
心室重构
心力衰竭
斑点追踪超声心动图
单变量分析
多元分析
作者
Damien Legallois,Amir Hodžić,Paul Milliez,Alain Manrique,Charles Dolladille,Éric Saloux,Farzin Beygui
摘要
Abstract Background Left ventricular remodeling (LVR) is common and associated with adverse outcome after ST‐elevation myocardial infarction (STEMI). We aimed to investigate the association between left atrial (LA) mechanical function using speckle tracking imaging and early LVR at follow‐up in STEMI patients. Methods Baseline 3D thoracic echocardiograms were performed within 48 h following admission and at a median follow‐up of 7 months after STEMI. A > 20% increase in the left ventricular (LV) end‐diastolic volume compared to baseline at follow‐up was defined as LVR. LA global longitudinal strain was evaluated for the reservoir, conduit, and contraction (LASct) phases. Results A total of 121 patients without clinical heart failure (HF) were prospectively included, between June 2015 and October 2018 (age 58.3 ± 12.5 years, male 98 (81%)). Baseline and follow‐up LV ejection fraction (LVEF) were 46.8% [41.0, 52.9] and 52.1% [45.8, 57.0] respectively ( p < .001). Compared to other patients, those with LVR had significantly lower values of LASct at baseline (−7.4% [−10.1, −6.5] vs. −9.9% [−12.8, −8.1], p < .01), both on univariate and baseline LV volumes‐adjusted analyses. Baseline LA strain for reservoir and conduit phases were not associated with significant LVR at follow‐up. Intra‐ and interobserver analysis showed good reproducibility of LA strain. Conclusions Baseline LASct may help identifying patients without HF after STEMI who are at higher risk of further early LVR and subsequent HF and who may benefit from more intensive management.
科研通智能强力驱动
Strongly Powered by AbleSci AI