Dietary calcium intake and the risk of stroke: Meta-analysis of cohort studies

医学 荟萃分析 前瞻性队列研究 冲程(发动机) 队列研究 相对风险 内科学 置信区间 队列 低风险 人口 人口学 环境卫生 机械工程 工程类 社会学
作者
Ze‐Mu Wang,Xinxin Bu,Bo Zhou,Yafei Li,Zhenlin Nie
出处
期刊:Nutrition Metabolism and Cardiovascular Diseases [Elsevier]
卷期号:33 (5): 934-946 被引量:2
标识
DOI:10.1016/j.numecd.2023.02.020
摘要

Prospective cohorts are inconsistent regarding the association between dietary calcium intake and the risk of stroke. The aim was to perform a meta-analysis to determine whether an association exists between them in cohort studies.Relevant studies were identified by searching PubMed, EMBASE and Web of Science databases that published before December 2022. Prospective cohort studies that provided relative risk (RR) estimates with 95% confidence intervals (CIs) for the association were included. Study-specific risk estimates were combined by using a random effects model. Eighteen prospective studies, including 19,557 stroke cases among 882,181 participants, were pooled in the meta-analysis. We observed a nonlinear association between calcium intake and risk of stroke (Pnonlinearity < 0.003). Compared with the lowest value of zero assumed as the reference, the RRs (95% CI) of stroke across levels of calcium intake were 0.95 (0.92, 0.98) for 200 mg/day, 0.94 (0.90, 0.98) for 300 mg/day, 0.95 (0.90, 0.99) for 500 mg/day, 0.98 (0.93, 1.03) for 700 mg/day, and 1.04 (0.97, 1.11) for 1000 mg/day. The stratified analyses by geographic region showed nonlinear associations and indicated that the protective effect was observed in Asian countries (Pnonlinearity = 0.001) but not in non-Asian regions (Pnonlinearity = 0.047).This meta-analysis suggests that dietary calcium intake might play an effective role in the prevention of stroke, especially in Asian countries. Future research among Asia population should attempt to establish whether this association is causal.PROSPERO CRD42022357710.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
风趣的含海完成签到,获得积分10
刚刚
桐桐应助stellafreeman采纳,获得30
1秒前
Gaopkid发布了新的文献求助10
1秒前
kuiuLinvk完成签到,获得积分10
2秒前
4秒前
6秒前
谦让夜香发布了新的文献求助10
7秒前
北秋完成签到,获得积分20
7秒前
暖暖发布了新的文献求助10
8秒前
我是老大应助hhh采纳,获得10
9秒前
波波发布了新的文献求助10
12秒前
xxxx完成签到,获得积分10
13秒前
13秒前
英姑应助暖暖采纳,获得10
15秒前
16秒前
神勇芝麻完成签到,获得积分10
17秒前
张小小完成签到,获得积分10
18秒前
华仔应助hhh采纳,获得10
18秒前
Tony完成签到,获得积分10
19秒前
20秒前
SS发布了新的文献求助10
20秒前
stellafreeman发布了新的文献求助30
21秒前
小霞完成签到 ,获得积分10
21秒前
21秒前
21秒前
kaneki发布了新的文献求助10
21秒前
小呵点完成签到 ,获得积分10
23秒前
oceanic发布了新的文献求助10
26秒前
水三寿发布了新的文献求助10
27秒前
sun发布了新的文献求助10
28秒前
骰子Zzz发布了新的文献求助10
28秒前
陶醉大侠完成签到,获得积分10
29秒前
30秒前
司马惜儿发布了新的文献求助10
31秒前
32秒前
彭于晏应助今天不吃饭采纳,获得10
32秒前
Orange应助无绮采纳,获得10
34秒前
如梦华完成签到 ,获得积分10
34秒前
搜集达人应助Ting采纳,获得10
34秒前
嗯哼应助韭菜何子采纳,获得20
35秒前
高分求助中
Sustainability in Tides Chemistry 1500
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
CLSI EP47 Evaluation of Reagent Carryover Effects on Test Results, 1st Edition 800
Threaded Harmony: A Sustainable Approach to Fashion 799
Livre et militantisme : La Cité éditeur 1958-1967 500
Retention of title in secured transactions law from a creditor's perspective: A comparative analysis of selected (non-)functional approaches 500
"Sixth plenary session of the Eighth Central Committee of the Communist Party of China" 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3055485
求助须知:如何正确求助?哪些是违规求助? 2712292
关于积分的说明 7430453
捐赠科研通 2357116
什么是DOI,文献DOI怎么找? 1248604
科研通“疑难数据库(出版商)”最低求助积分说明 606750
版权声明 596093