Electrochemical modification of a carbon paste electrode with poly (1,5‐diaminonaphthalene) and copper‐cobalt nanostructures for the determination of thioctic acid in real samples

Abstract This study used square‐wave voltammetry and cyclic voltammetry to investigate the electrochemical oxidation of Thioctic Acid (TA) on a Carbon Paste Electrode (CPE) modified with copper‐cobalt nanostructures and poly (1,5‐Diaminonaphthalene). The voltammetric sensor was sensitive to the oxidation of TA. In addition, we optimized the effects of multiple cycles of deposition of Cu‐Co nanostructures, and electro‐polymerization of monomer 1,5‐DAN, scan rate, and pH. The sensor showed good identification capabilities for TA. The linear responses obtained ranged from 0.6 μM to 150 μM with a detection limit of 0.48 μM for the modified CPE. The adsorption process controlled the oxidation of TA. We used the proposed sensor and method to determine TA in real samples.