免疫性血小板减少症
免疫系统
内科学
孟德尔遗传
医学
免疫学
生物
血小板
遗传学
基因
作者
J. Li,Nana Wang,Chen Huang,Yizhi Jiang,Dongping Huang
出处
期刊:PubMed
日期:2024-07-01
卷期号:54 (4): 430-445
摘要
Immune thrombocytopenia (ITP) is a common bleeding disorder. Although global lipidomic analyses have identified a potential role for lipid species in platelet function, there is currently no evidence to support a causal relationship between plasma lipids and ITP. To investigate this further, we conducted a two-sample Mendelian randomization analysis to determine whether there is a genetically predicted causal relationship between 179 plasma lipid groups and ITP.
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