Burden and Temporal Trends of Valvular Heart Disease‐Related Heart Failure From 1990 to 2019 and Projection Up to 2030 in Group of 20 Countries: An Analysis for the Global Burden of Disease Study 2019

Background The aim of this study was to characterize the burden of valvular heart disease (VHD)‐related heart failure (HF) in Group of 20 (G20) countries. Methods and Results Using data from the 2019 Global Burden of Disease Study, we estimated VHD‐related HF burdens (cases, age‐standardized prevalence rates, and years lived with disabilities rates) in G20 countries from 1990 to 2019 by age, sex, and sociodemographic index. The burden of VHD‐related HF increased in G20 countries from 1990 to 2019, exhibiting heterogeneity across VHD subtypes. In 2019, Italy, the United States, and the Russian Federation had the highest age‐standardized prevalence rates of nonrheumatic VHD‐related HF, whereas India, Brazil, and Mexico had the lowest. Rheumatic VHD‐related HF was most prevalent in China, India, and Italy, whereas the Republic of Korea, Brazil, and Turkey had the lowest. Nonrheumatic VHD‐related HF prevalence peaked among G20 countries in individuals ≥85 years of age, whereas rheumatic VHD‐related HF peaked in those 75 to 84 years of age in several countries, including China, India, the Russian Federation, Mexico, Argentina, and Turkey. Age‐standardized prevalence rates of nonrheumatic VHD‐related HF showed a decreasing trend, more pronounced in women, whereas rheumatic VHD‐related HF increased in both sexes, with a lower increase in men. Nonrheumatic VHD‐related HF burden correlated with age and sociodemographic index, whereas rheumatic VHD‐related HF burden was highest in middle sociodemographic index countries for those <75 years of age. Years lived with disabilities rates for VHD‐related HF represented about 9.0% of the overall burden across populations. Conclusions The increasing burden of VHD‐related HF in G20 countries highlights the need for timely interventions to mitigate this growing public health challenge.