Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries

生物单倍型全基因组关联研究遗传谱系 1000基因组计划遗传混合祖先信息标记等位基因遗传建筑学遗传学遗传关联进化生物学等位基因频率单核苷酸多态性基因人口基因型数量性状位点人口学社会学

作者

Bryan R. Gorman,Georgios Voloudakis,Robert P. Igo,Tyler G. Kinzy,Christopher Halladay,Tim B. Bigdeli,Biao Zeng,Sanan Venkatesh,Jessica N. Cooke Bailey,Dana C. Crawford,Kyriacos Markianos,Frederick N. Dong,Patrick Schreiner,Wen Zhang,Lars G. Fritsche,Wilmar Igl,Jessica N. Cooke Bailey,Felix Grassman,Sebanti Sengupta,Jennifer L. Bragg‐Gresham,Kathryn P. Burdon,Scott J. Hebring,Cindy Wen,Mathias Gorski,Ivana K. Kim,David Cho,Donald J. Zack,Eric H. Souied,Hendrik P. N. Scholl,Elisa Bala,Kristine E. Lee,David J. Hunter,Rebecca J. Sardell,Paul Mitchell,Joanna E. Merriam,Valentina Cipriani,Joshua Hoffman,Tina Schick,Yara T. E. Lechanteur,Robyn H. Guymer,Matthew P. Johnson,Yingda Jiang,Chloë M. Stanton,Gabriëlle H.S. Buitendijk,Xiaowei Zhan,Alan M. Kwong,Alexis Boleda,Matthew Brooks,Linn Gieser,Rinki Ratnapriya,Kari Branham,Johanna R. Foerster,John R. Heckenlively,Mohammad Othman,Brendan J. Vote,Helena Liang,Emmanuelle Souzeau,Ian L. McAllister,Timothy Isaacs,Janette M. Hall,Stewart Lake,David A. Mackey,Ian J. Constable,Jamie E. Craig,Terrie Kitchner,Zhenglin Yang,Ziying Su,Hongrong Luo,Daniel Chen,Ouyang Ouyang,Ken Flagg,Daniel Lin,Guanping Mao,Henry Ferreyra,Klaus Stark,Claudia N. von Strachwitz,Armin Wolf,Caroline Brandl,Guenther Rudolph,Matthias Olden,Margaux A. Morrison,D. H. Morgan,Matthew Schu,Jeeyun Ahn,Giuliana Silvestri,Evangelia E. Tsironi,Kyu Hyung Park,Lindsay A. Farrer,Anton Orlin,Alexander J. Brucker,Mingyao Li,Christine A. Curcio,Saddek Mohand‐Saïd,José‐Alain Sahel,Isabelle Audo,Mustapha Benchaboune,Angela J. Cree,Christina Rennie,Srinivas Goverdhan,Michelle Grunin,Shira Hagbi-Levi,Peter A. Campochiaro,Nicholas Katsanis,Frank G. Holz,Frédéric Blond,Hélène Blanché,Jean‐François Deleuze,Robert P. Igo,Barbara Truitt,Stacy M. Meuer,Chelsea E. Myers,Emily Moore,Ronald Klein,Michael A. Hauser,Eric A. Postel,Monique D. Courtenay,Stephen G. Schwartz,Jaclyn L. Kovach,William K. Scott,Gerald Liew,Ava Grace Tan,Bamini Gopinath,John C. Merriam,R. Theodore Smith,Jane C. Khan,Humma Shahidi,Anthony T. Moore,Josephine A. McGrath,Reneé Laux,Milam A. Brantley,Anita Agarwal,Lebriz Ersoy,Albert Caramoy,Thomas Langmann,Nicole T.M. Saksens,Eiko K. deJohn,Carel B. Hoyng,Melinda Cain,Andrea J. Richardson,Tammy M. Martin,John Blangero,Daniel E. Weeks,Bal Dhillon,Cornelia M. van Duijn,Kimberly F. Doheny,Jane Romm,Caroline C. W. Klaver,Caroline Hayward,Michael B. Gorin,Michael L. Klein,Paul N. Baird,Anneke I. den Hollander,Sascha Fauser,John R.W. Yates,Rando Allikmets,Jie Jin Wang,Debra A. Schaumberg,Ronald Klein,Stephanie A. Hagstrom,Itay Chowers,Andrew Lotery,Thierry Léveillard,Kang Zhang,Murray H. Brilliant,Alex W. Hewitt,Anand Swaroop,Emily Y. Chew,Margaret A. Pericak‐Vance,Margaret M. DeAngelis,Dwight Stambolian,J. L. Haines,Sudha K. Iyengar,Bernhard H. F. Weber,Gonçalo R. Abecasis,Iris M. Heid,Tamer Hadi,Matthew D. Anger,Amy Stockwell,Ronald B. Melles,Jie Yin,Hélène Choquet,Rebecca Kaye,Karina Patasova,Praveen J. Patel,Brian L. Yaspan,Eric Jorgenson,Pirro G. Hysi,Andrew Lotery,J. Michael Gaziano,Philip S. Tsao,Steven J. Fliesler,Jack M. Sullivan,Paul B. Greenberg,Wen‐Chih Wu,Themistocles L. Assimes,Saiju Pyarajan,Panos Roussos,Neal S. Peachey,Sudha K. Iyengar

出处

期刊：Nature Genetics [Springer Nature]
日期：2024-12-01 卷期号：56 (12): 2659-2671

链接

nih.govdoi.org

标识

DOI：10.1038/s41588-024-01764-0

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Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries

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