CD11b deficiency attenuates the ischemia/reperfusion‐induced AKI‐to‐CKD process by regulating macrophage polarization

Severe acute kidney injury (AKI) is a risk factor for the future development of chronic kidney disease (CKD), and macrophages are an essential cell group implicated in injury, repair, and fibrosis during this progress. However, the underlying mechanism of how macrophages participate in the development of the disease is largely unclear. CD11b (Integrin α